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Authors: Raif S. Geha, Luigi D. Notarangelo
Publisher: W. W. Norton & Company / Garland Science (7th Edition, 2021) · Language: English · ISBN-13: 978-1324033301
Case Studies in Immunology: A Clinical Companion by Raif S. Geha and Luigi D. Notarangelo is a leading resource that bridges foundational immunology with clinical practice. This text presents real-world case studies that illustrate how immunological principles explain the causes, progression, and treatment of immune-related diseases.
Designed as a companion to Janeway’s Immunobiology and Kuby Immunology, this edition provides a practical, patient-centered understanding of immune system function and dysfunction. Through carefully selected cases, students and practitioners gain insights into both common and rare immunological disorders, connecting theory directly to diagnosis and therapy.
Understand the key mechanisms of immune system function and how their disruption leads to disease.
Examine primary and secondary immunodeficiencies, including genetic and acquired conditions that impair immune responses.
Learn how failures in immune regulation lead to diseases such as systemic lupus erythematosus, rheumatoid arthritis, and type 1 diabetes.
Study the mechanisms behind allergic reactions, hypersensitivity, and immune-mediated inflammation.
Explore how the immune system combats pathogens and tumor cells—and how immunotherapies are designed to enhance these responses.
Understand how clinical immunology informs the development of treatments such as gene therapy, monoclonal antibodies, and immune modulators.
Case Studies in Immunology transforms theoretical knowledge into clinical insight. Each case provides a real-world perspective, complete with background information, laboratory data, molecular mechanisms, and therapeutic considerations.
This approach makes it an invaluable tool for learning how immunological principles apply to patient care, diagnosis, and treatment. The text encourages analytical thinking and helps readers integrate immunological science with clinical reasoning.
Medical, Nursing, and Health Science Students seeking to apply immunology in clinical settings.
Undergraduate and Graduate Students studying immunology, biomedicine, or related fields.
Educators and Researchers using clinical examples to teach immune mechanisms.
Healthcare Professionals interested in understanding immune disorders and their management.
Primary and secondary immunodeficiencies
Autoimmunity and immune tolerance
Allergies and hypersensitivity reactions
Immune responses to infections and tumors
Inborn errors of immunity
Immunotherapy and gene therapy
Cytokine signaling and molecular mechanisms of disease
Case-based learning and diagnostic reasoning
Case Studies in Immunology: A Clinical Companion offers an engaging and clinically relevant approach to understanding the immune system in health and disease. By combining detailed case studies with concise explanations of underlying mechanisms, it bridges the gap between theoretical immunology and real-world medicine.
Whether used alongside a core immunology textbook or as a standalone clinical reference, Geha and Notarangelo’s work remains an essential resource for students, educators, and clinicians aiming to connect immunological science with patient-centered care.
